Lowering the pH into a range of 4-6 results in HOCl as the dominant species and a pH similar to intact human skin. As a result, the activity increases by a factor of 80-100 times that observed in higher-pH solutions such as Dakin's, while the lower pH apparently eliminates cytotoxicity and confers sporicidal activity.1,2
Vashe Wound Solution, powered by a proprietary electrochemical process called Natural Zone Technology 5.5, is titrated to a skin-friendly pH of 5.5 to mimic the body's natural antimicrobial defenses and provide an ideal healing environment.
Vashe Wound Solution has been tested against many common pathogens, including fungi, spores, and multi-drug-resistant bacterial strains.5-7SEE THE RESULTS
For more in-depth information about the Vashe difference, please see the following resource.
1. Block SS, ed. Disinfection, sterilization, and preservation. Philadelphia: Lea & Febiger; 2000. 2. Wang L, et al: Hypochlorous acid as a potential would care agent: Part I, Stabilized hypochlorous acid: A component of the inorganic armamentarium of innate immunity. J Burns Wounds. 2007;6:65-79. 3. Robson MC. Treating chronic wounds with hypochlorous acid disrupts biofilm. Today's Wound Clinic. November/December. 4. Miller C, Mouhlas A.Significant cost savings realized by changing debridement protocol. Ostomy Wound Manage. 2014;9:9-8. 5. Vashe Would Solution data developed from USP 51 Antimicrobial testing. 6. Bohn GA et al. Can the use of hypochlorous acid change your dressing selection? Poster Presentation: Symposium for Advanced Wound Care; 2013; Orlando, FL. 7. Nerandzic MM, Rackaityte E, Jury LA, Eckart K, Donksey CJ. Novel Strategies for Enhanced Removal of Persistent Bacillus anthracis Surrogates and Clostridium difficile Spores from Skin. PLoS One. 2013;8(7):e68706. doi:10.1371/journal.pone.0068706.